Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582899 | 0.85 | PTAFR (0.62) | PTAFR | |
| SCHEMBL9300543 | 0.83 | TNF (0.67) | PTAFR | |
| SCHEMBL9049974 | 0.83 | GALR3 (0.50) | PTAFR | |
| SCHEMBL7498482 | 0.83 | GALR3 (0.50) | PTAFR | |
| Bromide SCHEMBL9054549 | 0.82 | GALR3 (0.49) | PTAFR | |
| SCHEMBL9051522 | 0.80 | GALR3 (0.52) | PTAFR | |
| SCHEMBL7497522 | 0.80 | GALR3 (0.68) | PTAFR | |
| SCHEMBL9051695 | 0.80 | GALR3 (0.50) | PTAFR | |
| SCHEMBL7496777 | 0.80 | MEN1 (0.57) | PTAFR | |
| SCHEMBL9050044 | 0.80 | PTAFR (0.48) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635018-B1 | 4-(1H-2-METHYLIMIDAZO[4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO TECHNOLOGY (GB) | 1999-12-22 | — | — | EP | disclosed |
| US-5516783-A | PLATELET ACTIVATING FACTOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-05-14 | — | — | US | disclosed |
| WO-1993016075-A1 | 4-(1H-2-METHYLIMIDAZO[4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-19 | — | — | WO | disclosed |
| EP-0543861-A1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| US-5180723-A | Hypertensives, bronchodilators, antiedemic agents | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-01-19 | — | — | US | disclosed |
| WO-1992003422-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |