Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 2/20 | 0.75 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.49 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2219585 | 0.91 | CHKA (0.83) | CHKANR4A2SOS2LMNASMN1; SMN2 | |
| SCHEMBL10062533 | 0.87 | CHKA (0.77) | CHKANR4A2SOS2LMNASMN1; SMN2 | |
| SCHEMBL13450995 | 0.86 | CHKA (0.75) | CHKANR4A2SOS2LMNASMN1; SMN2 | |
| SCHEMBL11136934 | 0.86 | CHKA (1.00) | CHKANR4A2SOS2LMNASMN1; SMN2 | |
| SCHEMBL1706258 | 0.79 | CHKA (0.68) | CHKANR4A2SOS2LMNASMN1; SMN2 | |
| SCHEMBL30058586 | 0.79 | CHKA (0.68) | CHKANR4A2SOS2LMNASMN1; SMN2 | |
| SCHEMBL30522270 | 0.77 | CHKA (0.69) | CHKALMNACYP1A2HSD17B10MAPT | |
| SCHEMBL610392 | 0.77 | CHKA (0.69) | CHKALMNACYP1A2HSD17B10MAPT | |
| SCHEMBL21346926 | 0.76 | CHKA (0.70) | CHKANR4A2SOS2LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10573768 | 0.75 | CHKA (0.62) | CHKANR4A2SOS2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |