Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14415230 | 0.92 | SLC7A5 (0.51) | SLC7A5CYP4F2CYP4A11LOXL2STAT3 | |
| SCHEMBL5467067 | 0.85 | CYP4F2 (0.64) | SLC7A5CYP4F2CYP4A11LOXL2CA12 | |
| SCHEMBL3126755 | 0.83 | CA1 (0.48) | SLC7A5CYP4F2CYP4A11STAT3CA12 | |
| SCHEMBL7646280 | 0.83 | SLC7A5 (0.43) | SLC7A5CYP4F2CYP4A11STAT3NR3C1 | |
| SCHEMBL15000874 | 0.83 | CYP4F2 (0.52) | SLC7A5CYP4F2CYP4A11LOXL2CA2 | |
| SCHEMBL14992864 | 0.83 | CYP4F2 (0.63) | CYP4F2CYP4A11CA12CA1CA14 | |
| SCHEMBL31487557 | 0.80 | CYP4F2 (0.69) | SLC7A5CYP4F2CYP4A11LOXL2STAT3 | |
| SCHEMBL5382573 | 0.80 | SLC7A5 (0.60) | SLC7A5CYP4F2CYP4A11LOXL2STAT3 | |
| SCHEMBL7505386 | 0.80 | CYP4F2 (0.69) | SLC7A5CYP4F2CYP4A11LOXL2STAT3 | |
| SCHEMBL7504785 | 0.79 | SLC7A5 (0.63) | SLC7A5CYP4F2CYP4A11LOXL2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206265-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1206265-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001000213-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |