Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5945687 | 1.00 | DRD2 (1.00) | DRD2 | |
| SCHEMBL5945738 | 1.00 | DRD2 (1.00) | DRD2 | |
| SCHEMBL8672337 | 0.84 | DRD2 (0.72) | DRD2 | |
| SCHEMBL8672335 | 0.84 | DRD2 (0.72) | DRD2 | |
| SCHEMBL8672340 | 0.84 | DRD2 (0.72) | DRD2 | |
| SCHEMBL8875861 | 0.83 | DRD2 (0.71) | DRD2 | |
| SCHEMBL8875869 | 0.83 | DRD2 (0.71) | DRD2 | |
| SCHEMBL8875872 | 0.83 | DRD2 (0.71) | DRD2 | |
| Hydrochloric Acid SCHEMBL7926859 | 0.83 | DRD2 (0.70) | DRD2 | |
| Hydrochloric Acid SCHEMBL7926863 | 0.83 | DRD2 (0.70) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020035998-A1 | Method for treatment of cancer and infectious disease | HELLSTRAND KRISTOFFER (SE) | 2002-03-28 | — | — | US | claimed |
| US-6305380-B1 | ADMINISTERING HISTAMINE AGONIST OR HT3 RECEPTOR ANTAGONIST TO ACTIVATE NATURAL KILLER CELLS AND TREAT VIRAL DISEASES | MAXIM PHARMACEUTICALS, INC. | 2001-10-23 | — | — | US | claimed |
| EP-0652768-B1 | A pharmaceutical preparation for the synergistic activation of natural killer cells | MAXIM PHARM INC (US) | 2000-05-03 | — | — | EP | claimed |
| US-5728378-A | ANTITUMOR AND ANTIVIRUS AGENTS | MAXIM PHARMACEUTICALS, INC. (US) | 1998-03-17 | — | — | US | claimed |
| US-20020035998-A1 | Method for treatment of cancer and infectious disease | HELLSTRAND KRISTOFFER (SE) | 2002-03-28 | — | — | US | disclosed |
| US-6331636-B1 | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, DIABETES, HYPERTENSION, IMPOTENCY, APPETITE CONTROL | THE UPJOHN COMPANY | 2001-12-18 | — | — | US | disclosed |
| US-6305380-B1 | ADMINISTERING HISTAMINE AGONIST OR HT3 RECEPTOR ANTAGONIST TO ACTIVATE NATURAL KILLER CELLS AND TREAT VIRAL DISEASES | MAXIM PHARMACEUTICALS, INC. | 2001-10-23 | — | — | US | disclosed |
| US-6155266-A | Method for treatment of cancer and infectious disease | MAXIM PHARMACEUTICALS, INC. (US) | 2000-12-05 | — | — | US | disclosed |
| EP-0652768-B1 | A pharmaceutical preparation for the synergistic activation of natural killer cells | MAXIM PHARM INC (US) | 2000-05-03 | — | — | EP | disclosed |
| US-6003516-A | Method for treatment of cancer and infectious disease | MAXIM PHARMACEUTICALS, INC. (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0476016-B1 | CNS active 8-heterocyclyl-2-aminotetralin derivatives | UPJOHN CO (US) | 1998-10-28 | — | — | EP | disclosed |
| US-5728378-A | ANTITUMOR AND ANTIVIRUS AGENTS | MAXIM PHARMACEUTICALS, INC. (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0586525-A1 | CARBOXAMIDO-(1,2N)-CARBOCYCLIC-2-AMINOTETRALIN DERIVATIVES. | UPJOHN CO (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0552246-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 1993-07-28 | — | — | EP | disclosed |
| WO-1992021654-A2 | CARBOXAMIDO-(3,2N)-CARBOCYCLIC-2-AMINOTETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1992-12-10 | — | — | WO | disclosed |
| WO-1992020655-A1 | CARBOXAMIDO-(1,2N)-CARBOCYCLIC-2-AMINOTETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1992-11-26 | — | — | WO | disclosed |
| WO-1992006967-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1992-04-30 | — | — | WO | disclosed |
| EP-0476016-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |
| WO-1991000856-A2 | (1,2N) AND (3,2N)-CARBOCYCLIC-2-AMINO TETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1991-01-24 | — | — | WO | disclosed |
| WO-1990015047-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1990-12-13 | — | — | WO | disclosed |