Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10923518 | 0.83 | KMT2A (0.53) | L3MBTL1CYP3A4MAPTKDM4EALDH1A1 | |
| SCHEMBL4544920 | 0.81 | TDP1 (0.48) | ATMTDP1L3MBTL1HSD17B10RAB9A | |
| SCHEMBL735728 | 0.79 | TDP1 (0.47) | ATMTDP1L3MBTL1HSD17B10RAB9A | |
| SCHEMBL10962554 | 0.78 | KMT2A (0.56) | TDP1L3MBTL1HSD17B10NPC1CYP1A2 | |
| SCHEMBL10411906 | 0.77 | TDP1 (0.45) | ATMTDP1L3MBTL1HSD17B10RAB9A | |
| SCHEMBL505224 | 0.77 | THRA (0.49) | ATMTDP1L3MBTL1HSD17B10RAB9A | |
| SCHEMBL5954678 | 0.76 | HSD17B10 (0.40) | ATMTDP1L3MBTL1HSD17B10NPC1 | |
| SCHEMBL29211141 | 0.76 | TDP1 (0.44) | ATMTDP1L3MBTL1HSD17B10RAB9A | |
| SCHEMBL9190844 | 0.76 | THRA (0.47) | ATMTDP1L3MBTL1HSD17B10RAB9A | |
| SCHEMBL27737478 | 0.76 | THRA (0.47) | ATMTDP1L3MBTL1HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114516824-A | Thioamide carboxylic ester and synthetic method thereof | 广州佳途科技股份有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-110372582-A | A kind of synthesis technology of betrixaban | 江苏恒盛药业有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-114516824-A | Thioamide carboxylic ester and synthetic method thereof | 广州佳途科技股份有限公司 | 2022-05-20 | — | — | CN | disclosed |
| EP-0911335-B1 | Method for producing furopyridine derivatives and intermediate compounds | KURARAY CO (JP) | 2002-04-17 | — | — | EP | disclosed |
| EP-0893436-B1 | Process for producing cyanoformate esters | CREANOVA INC (US) | 2002-03-27 | — | — | EP | disclosed |
| US-6342606-B2 | REACTING PYRIDINE ESTER DERIVATIVE WITH A REDUCING AGENT, AN ALKYLATING AGENT, AN ALKENYLATING AGENT, AN ARYLATING AGENT OR AN ARALKYLATING AGENT TO OBTAIN A PYRIDINE CARBONYL DERIVATIVE, REDUCING | KURARAY CO., LTD. (JP) | 2002-01-29 | — | — | US | disclosed |
| US-20010031871-A1 | Method for producing pyridine derivatives | KURARAY CO., LTD. (JP) | 2001-10-18 | — | — | US | disclosed |
| US-6265580-B1 | REACTING AMINE DERIVATIVE WITH CARBONYLATING AGENT AND NITRILE DERIVATIVE | KURARAY CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6111111-A | Intermediates for producing pyridine derivatives | KURARAY CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0911335-A2 | Method for producing furopyridine derivatives and intermediate compounds | KURARAY CO., LTD. (JP) | 1999-04-28 | — | — | EP | disclosed |
| EP-0893436-A1 | Process for producing cyanoformate esters | Creanova Inc. (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5852207-A | Process for producing cyanoformate esters | CREANOVA INC. (US) | 1998-12-22 | — | — | US | disclosed |
| US-3986973-A | CYANOFORMATES AND CYANOFORMAMIDES AS BLEACH ACTIVATORS | AMERICAN CYANAMID COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031871-A1 | Method for producing pyridine derivatives | CYP2E1, CBR1, CBR3 | ATM 2644/4885TDP1 3188/4885L3MBTL1 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.