Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499330 | 1.00 | KMT2A (0.68) | KMT2AMEN1GAAMAPTPOLB | |
| SCHEMBL3500377 | 0.88 | MAPT (0.63) | KMT2AMEN1GAAMAPTPOLB | |
| SCHEMBL7490971 | 0.88 | MAPT (0.63) | KMT2AMEN1GAAMAPTPOLB | |
| SCHEMBL7488228 | 0.88 | MAPT (0.63) | KMT2AMEN1GAAMAPTPOLB | |
| SCHEMBL7493115 | 0.88 | MAPT (0.63) | KMT2AMEN1GAAMAPTPOLB | |
| SCHEMBL7494893 | 0.88 | GAA (0.61) | KMT2AMEN1GAAMAPTPOLB | |
| SCHEMBL7494886 | 0.88 | GAA (0.61) | KMT2AMEN1GAAMAPTPOLB | |
| SCHEMBL7501001 | 0.88 | TDP1 (0.64) | KMT2AMEN1GAAMAPTPOLB | |
| SCHEMBL7500985 | 0.88 | TDP1 (0.64) | KMT2AMEN1GAAMAPTPOLB | |
| SCHEMBL7492794 | 0.84 | GAA (0.57) | KMT2AMEN1GAAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638075-B1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| US-5677322-A | THERAPY FOR AGING, DIABETES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |