Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501001 | 1.00 | TDP1 (0.64) | TDP1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7493115 | 0.90 | MAPT (0.63) | TDP1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7488228 | 0.90 | MAPT (0.63) | TDP1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL3500377 | 0.90 | MAPT (0.63) | TDP1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7490971 | 0.90 | MAPT (0.63) | TDP1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7490272 | 0.89 | L3MBTL1 (0.70) | TDP1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7490274 | 0.89 | L3MBTL1 (0.70) | TDP1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7494297 | 0.89 | MAPT (0.60) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL7494293 | 0.89 | MAPT (0.60) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL7491013 | 0.88 | MAPT (0.59) | MAPTMEN1KMT2AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638075-B1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| EP-0638075-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994019335-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |