SCHEMBL7499362

SCHEMBL7499362

C=C(C)C(=O)NC1=NN(c2c(Cl)cc(Cl)cc2Cl)C(=O)C1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.60
L3MBTL1 Q9Y468 5/20 0.60
RECQL P46063 4/20 0.60
POLB P06746 4/20 0.60
BLM P54132 2/20 0.60
KMT2A Q03164 7/20 0.53
MEN1 O00255 6/20 0.53
MAPT P10636 6/20 0.53
THRB P10828 1/20 0.53
HTT P42858 1/20 0.53
ALOX12 P18054 1/20 0.42
GRK5 P34947 1/20 0.39
CDK8 P49336 1/20 0.39
TDP1 Q9NUW8 4/20 0.38
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
ALDH1A1 P00352 2/20 0.36
MAPK1 P28482 1/20 0.33
KDM4E B2RXH2 2/20 0.33
CASP6 P55212 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9344030 0.87 MEN1 (0.57) GAAL3MBTL1RECQLPOLBBLM
SCHEMBL11047439 0.85 MEN1 (0.72) GAAL3MBTL1RECQLPOLBBLM
SCHEMBL11069491 0.85 POLB (0.47) GAAL3MBTL1RECQLPOLBBLM
SCHEMBL11201527 0.84 GAA (0.60) GAAL3MBTL1RECQLPOLBBLM
SCHEMBL14400389 0.82 KMT2A (0.50) GAAL3MBTL1RECQLPOLBBLM
SCHEMBL7139296 0.82 GAA (0.60) GAAL3MBTL1RECQLPOLBBLM
SCHEMBL10870637 0.81 MAPT (0.53) GAAL3MBTL1RECQLPOLBBLM
SCHEMBL8428370 0.81 MEN1 (0.51) GAAL3MBTL1RECQLPOLBBLM
SCHEMBL8173684 0.81 MEN1 (0.53) GAAL3MBTL1RECQLPOLBBLM
SCHEMBL11578978 0.81 GAA (0.76) GAAL3MBTL1RECQLPOLBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675406-B1 A method of processing using a low volume thin tank processing system EASTMAN KODAK CO (US) 2002-10-09 EP disclosed
EP-0684517-B1 Photographic element with silver halide emulsion layer of low developability and having an associated high dye-yield coupler EASTMAN KODAK CO (US) 2002-07-24 EP disclosed
EP-0684514-B1 Tight-wrapped photographic element containing a high dye-yield coupler EASTMAN KODAK CO (US) 2002-07-17 EP disclosed
EP-0720047-B1 Photographic element containing a stable aryloxypyrazolone coupler and process employing the same EASTMAN KODAK CO (US) 2002-07-03 EP disclosed
EP-0953871-B1 Photographic element containing yellow dye-forming photographic coupler EASTMAN KODAK CO (US) 2002-06-26 EP disclosed
EP-0684516-B1 Photographic element containing a high dye-yield coupler with a methine dye chromophore EASTMAN KODAK CO (US) 2002-01-23 EP disclosed
EP-0718687-B1 Photographic element containing a novel cyan dye forming a coupler and process for its use EASTMAN KODAK CO (US) 2001-11-28 EP disclosed
EP-0953875-B1 Photographic element containing yellow coupler EASTMAN KODAK CO (US) 2001-10-31 EP disclosed
EP-0720048-B1 Photographic element containing pyrazolone pug releasing coupler and imaging process employing same EASTMAN KODAK CO (US) 2001-10-24 EP disclosed
EP-0718688-B1 Photographic element containing a novel cyan dye forming coupler and process for its use EASTMAN KODAK CO (US) 2001-10-10 EP disclosed
EP-0629913-A1 Photographic elements containing magenta couplers and process for using same EASTMAN KODAK COMPANY (US) 1994-12-21 EP disclosed
EP-0628868-A1 Photographic elements containing magenta couplers and process for using same EASTMAN KODAK COMPANY (US) 1994-12-14 EP disclosed
US-5372920-A Multilayer EASTMAN KODAK COMPANY (US) 1994-12-13 US disclosed
US-5350667-A Image forming silver halide emulsions with pyrazolone dyes EASTMAN KODAK COMPANY (US) 1994-09-27 US disclosed
US-5314792-A Multiple layers sensitized to green light, varying degrees of light sensitivity, color negative films, development inhibitor releasing couplers EASTMAN KODAK COMPANY (US) 1994-05-24 US disclosed
US-4668613-A POLYMERIC COUPLER FUJI PHOTO FILM CO. LTD. (JP) 1987-05-26 US disclosed
US-H156-H Silver halide color light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-11-04 US disclosed
EP-0133262-A2 Silver halide color light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-02-20 EP disclosed
US-4444870-A COPOLYMER COUPLER LATEX FUJI PHOTO FILM CO., LTD. (JP) 1984-04-24 US disclosed
US-4128427-A Silver halide emulsions containing polymeric color couplers AGFA-GEVAERT, N.V. (BE) 1978-12-05 US disclosed