Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498069 | 0.92 | ALDH1A1 (0.56) | ALDH1A1MT-CO2ALOX5POLBMEN1 | |
| SCHEMBL7497913 | 0.91 | ALDH1A1 (0.58) | ALDH1A1MT-CO2ALOX5POLBMEN1 | |
| SCHEMBL7507666 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MT-CO2ALOX5POLBMEN1 | |
| SCHEMBL7507674 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MT-CO2ALOX5POLBMEN1 | |
| SCHEMBL7503274 | 0.88 | ALDH1A1 (0.48) | ALDH1A1MT-CO2ALOX5POLBMEN1 | |
| SCHEMBL7501901 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MT-CO2ALOX5POLBMEN1 | |
| SCHEMBL7497354 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MT-CO2ALOX5POLBMEN1 | |
| SCHEMBL7497359 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MT-CO2ALOX5POLBMEN1 | |
| SCHEMBL7495513 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MT-CO2ALOX5POLBMEN1 | |
| SCHEMBL7498239 | 0.85 | ALDH1A1 (0.52) | ALDH1A1MT-CO2ALOX5POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757681-B1 | CONDENSED HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE AS GnRH ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-09-18 | — | — | EP | disclosed |