Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.62 |
| ▸ | PDE4A | P27815 | 15/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400233 | 0.89 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DSLC6A4 | |
| SCHEMBL7400235 | 0.89 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DSLC6A4 | |
| SCHEMBL7318584 | 0.88 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8879699 | 0.88 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7862279 | 0.87 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DSLC6A4 | |
| SCHEMBL7862294 | 0.87 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DSLC6A4 | |
| SCHEMBL7862283 | 0.87 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DSLC6A4 | |
| SCHEMBL6546408 | 0.87 | PDE4B (0.64) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7863406 | 0.86 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7416969 | 0.86 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995009836-A1 | CYANOCYCLOHEXANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 1995-04-13 | — | — | WO | claimed |