Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499479 | 1.00 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL8900432 | 1.00 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL7499477 | 1.00 | HTR1A (1.00) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8899390 | 0.99 | HTR1A (0.97) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8899386 | 0.99 | HTR1A (0.97) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8899396 | 0.99 | HTR1A (0.97) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8900488 | 0.99 | HTR1A (0.97) | HTR1ADRD2 | |
| SCHEMBL10756897 | 0.93 | HTR1A (0.86) | HTR1ADRD2 | |
| SCHEMBL10756886 | 0.93 | HTR1A (0.86) | HTR1ADRD2 | |
| SCHEMBL10756890 | 0.93 | HTR1A (0.86) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482084-B1 | (1,2N) AND (3,2N)-CARBOCYCLIC-2-AMINO TETRALIN DERIVATIVES | UPJOHN CO (US) | 1997-05-07 | — | — | EP | claimed |
| WO-1992021654-A2 | CARBOXAMIDO-(3,2N)-CARBOCYCLIC-2-AMINOTETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1992-12-10 | — | — | WO | disclosed |