Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958818 | 0.79 | KDM4E (0.47) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL8892465 | 0.79 | KDM4E (0.49) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL8892454 | 0.79 | KDM4E (0.49) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL4659586 | 0.78 | MEN1 (0.46) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL22835926 | 0.76 | NMBR (0.53) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL4121782 | 0.75 | PKM (0.50) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL4121788 | 0.75 | PKM (0.50) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL4132288 | 0.75 | PKM (0.50) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL343309 | 0.75 | MAPT (0.54) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL200589 | 0.75 | MAPT (0.54) | MAPTKDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086101-B1 | BETA-CARBOLINE COMPOUNDS | SOD CONSEILS RECH APPLIC (FR) | 2002-12-18 | — | — | EP | disclosed |