Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 19/20 | 0.39 |
| ▸ | CDK9 | P50750 | 19/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499179 | 0.87 | ALK (0.35) | CCNT1CDK9 | |
| SCHEMBL2064496 | 0.75 | ELANE (0.38) | CDK1 | |
| SCHEMBL2063435 | 0.69 | BTK (0.38) | CCNT1CDK9 | |
| SCHEMBL2063653 | 0.68 | TMEM97 (0.47) | CCNT1CDK9CDK1CDK2CDK8 | |
| SCHEMBL7503378 | 0.64 | CCNT1 (0.43) | CCNT1CDK9 | |
| SCHEMBL2063892 | 0.63 | ELANE (0.40) | CDK1 | |
| SCHEMBL30908939 | 0.61 | DAO (0.39) | — | |
| SCHEMBL2064707 | 0.61 | ELANE (0.43) | CDK1 | |
| SCHEMBL1445398 | 0.60 | MCHR1 (0.41) | — | |
| SCHEMBL2064461 | 0.60 | CDK7 (0.39) | CDK9CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204662-A1 | AZAINDOLES HAVING SEROTONIN RECEPTOR AFFINITY | NPS Allelix Corp. (CA) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012629-A1 | AZAINDOLES HAVING SEROTONIN RECEPTOR AFFINITY | NPS ALLELIX CORP. (US) | 2001-02-22 | — | — | WO | disclosed |