Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 5/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527004 | 1.00 | GNAI3 (0.38) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL6487784 | 0.88 | S1PR1 (0.37) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL30426265 | 0.83 | KDM4E (0.37) | — | |
| SCHEMBL6484393 | 0.79 | GBA1 (0.44) | GNAI3GNAO1GNAI1TAAR1GBA1 | |
| SCHEMBL28538299 | 0.78 | TSHR (0.38) | GNAI3GNAO1GNAI1TAAR1 | |
| SCHEMBL28180032 | 0.78 | TAAR1 (0.44) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL3106291 | 0.78 | TAAR1 (0.44) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL9261256 | 0.77 | GBA1 (0.43) | GNAI3GNAO1GNAI1TAAR1GBA1 | |
| SCHEMBL6566400 | 0.77 | TAAR1 (0.52) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL6439309 | 0.77 | TAAR1 (0.52) | GNAI3GNAO1GNAI1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187828-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000078748-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-12-28 | — | — | WO | disclosed |