Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CDK2 | P24941 | 1/20 | 0.59 |
| ▸ | CCR1 | P32246 | 1/20 | 0.58 |
| ▸ | FERMT2 | Q96AC1 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CCNC | P24863 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PAK4 | O96013 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12845437 | 0.82 | FADS1 (0.51) | CDK2CCNCCDK8POLBSLC2A1 | |
| SCHEMBL8045380 | 0.79 | POLB (0.56) | CDK2POLBSLC2A1RAD52KMT2A | |
| SCHEMBL7503073 | 0.78 | CCNC (0.81) | CYP1A2CCR1FERMT2PKMCCNC | |
| SCHEMBL7509946 | 0.78 | CYP1A2 (0.74) | CYP1A2CCR1FERMT2PKMKMT2A | |
| SCHEMBL8738060 | 0.78 | CYP1A2 (1.00) | CYP1A2CCR1FERMT2PKMKMT2A | |
| SCHEMBL12845502 | 0.77 | KMT2A (0.56) | CDK2POLBSLC2A1RAD52KMT2A | |
| SCHEMBL7501815 | 0.76 | CYP1A2 (0.62) | CYP1A2CCR1FERMT2PKMCCNC | |
| SCHEMBL7504915 | 0.76 | CYP1A2 (0.70) | CYP1A2CCR1FERMT2PKMKMT2A | |
| SCHEMBL27464469 | 0.76 | CYP1A2 (0.58) | CYP1A2CCR1FERMT2PKMCCNC | |
| SCHEMBL7508615 | 0.76 | KMT2A (0.57) | CDK2POLBSLC2A1RAD52KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | claimed |
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |