SCHEMBL7500035

SCHEMBL7500035

N#CC(CC(=O)O)NC(=O)[C@@H]1CCCN(C(=O)CCC2CCNCC2)C1

nearest known ligand 0.77

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 20/20 0.77
ITGA2B P08514 20/20 0.77
F2R P25116 12/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7502258 0.91 ITGB3 (0.78) ITGB3ITGA2BF2R
Hydrochloric Acid SCHEMBL7502178 0.90 ITGB3 (0.77) ITGB3ITGA2BF2R
Trifluoroacetic Acid SCHEMBL7498922 0.87 ITGB3 (0.72) ITGB3ITGA2BF2R
Trifluoroacetic Acid SCHEMBL7506277 0.87 ITGB3 (0.72) ITGB3ITGA2BF2R
SCHEMBL6538736 0.86 ITGB3 (0.79) ITGB3ITGA2BF2R
SCHEMBL6539830 0.86 ITGB3 (0.79) ITGB3ITGA2BF2R
Hydrochloric Acid SCHEMBL7502038 0.85 ITGB3 (0.78) ITGB3ITGA2BF2R
SCHEMBL6539540 0.85 ITGB3 (0.78) ITGB3ITGA2BF2R
SCHEMBL7502431 0.85 ITGB3 (1.00) ITGB3ITGA2BF2R
SCHEMBL8278503 0.85 ITGB3 (0.82) ITGB3ITGA2BF2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6380215-B1 FOR PREVENTION AND/OR TREATMENT OF DISEASES CAUSED BY THROMBUS FORMATION SUCH AS ARTERIAL THROMBOSIS, ARTERIAL SCLEROSIS, ISCHEMIC HEART DISEASES FUJISAWA PHARMACEUTICAL CO., LTD (JP) 2002-04-30 US disclosed
EP-0669912-B1 N-(3-PIPERIDINYLCARBONYL)-BETA-ALANINE DERIVATIVES AS PAF ANTAGONISTS FUJISAWA PHARMACEUTICAL CO (JP) 2001-12-05 EP disclosed
EP-1106606-A2 N-(3-piperidinylcarbonyl)-beta-alanine derivatives as paf antagonists FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-06-13 EP disclosed
EP-0669912-A1 N-(3-PIPERIDINYLCARBONYL)-BETA-ALANINE DERIVATIVES AS PAF ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-09-06 EP disclosed
WO-1995008536-A1 N-(3-PIPERIDINYLCARBONYL)-BETA-ALANINE DERIVATIVES AS PAF ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-03-30 WO disclosed