Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.78 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.78 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.78 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.78 |
| ▸ | CCNC | P24863 | 7/20 | 0.60 |
| ▸ | CDK8 | P49336 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.56 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507732 | 0.92 | HTR1A (0.70) | HTR1AADRA1DADRA1AADRA1BCCNC | |
| SCHEMBL27325782 | 0.92 | HTR1A (0.70) | HTR1AADRA1DADRA1AADRA1BCCNC | |
| SCHEMBL7502818 | 0.92 | HTR1A (0.74) | HTR1AADRA1DADRA1AADRA1BCCNC | |
| SCHEMBL7505406 | 0.90 | HTR1A (0.67) | HTR1AADRA1DADRA1AADRA1BCCNC | |
| SCHEMBL19160656 | 0.89 | CCNC (0.77) | HTR1AADRA1DADRA1AADRA1BCCNC | |
| SCHEMBL18290376 | 0.88 | HTR1A (1.00) | HTR1AADRA1DADRA1AADRA1BCCNC | |
| SCHEMBL7503774 | 0.86 | HTR1A (0.67) | HTR1AADRA1DADRA1AADRA1BCCNC | |
| SCHEMBL7510312 | 0.81 | CYP1A2 (0.70) | HTR1AADRA1DADRA1AADRA1BCCNC | |
| SCHEMBL21946633 | 0.81 | HTR1A (0.70) | HTR1AADRA1DADRA1AADRA1BCCNC | |
| SCHEMBL7505681 | 0.80 | CCNC (0.70) | HTR1AADRA1DADRA1AADRA1BCCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |