Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | F2R | P25116 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498599 | 0.95 | KMT2A (0.46) | ITGB3ITGA2BKMT2AHTTF2R | |
| SCHEMBL7492120 | 0.90 | ITGB3 (0.47) | ITGB3ITGA2BKMT2AF2RNPC1 | |
| SCHEMBL7498497 | 0.89 | ITGB3 (0.48) | ITGB3ITGA2BKMT2AF2RRAB9A | |
| SCHEMBL7496757 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2BF2RNPC1RAB9A | |
| SCHEMBL7501795 | 0.89 | ITGB3 (0.54) | ITGB3ITGA2BKMT2AF2RNPC1 | |
| Hydrochloric Acid SCHEMBL7498638 | 0.88 | ITGB3 (0.58) | ITGB3ITGA2BF2R | |
| SCHEMBL7846014 | 0.87 | ITGB3 (0.51) | ITGB3ITGA2BKMT2AF2RTSHR | |
| SCHEMBL7443415 | 0.86 | KMT2A (0.43) | KMT2AHTTNPC1RAB9ATSHR | |
| SCHEMBL7500224 | 0.86 | ITGB3 (0.53) | ITGB3ITGA2BF2R | |
| SCHEMBL7503555 | 0.86 | ITGB3 (0.47) | ITGB3ITGA2BKMT2AF2RKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380215-B1 | FOR PREVENTION AND/OR TREATMENT OF DISEASES CAUSED BY THROMBUS FORMATION SUCH AS ARTERIAL THROMBOSIS, ARTERIAL SCLEROSIS, ISCHEMIC HEART DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2002-04-30 | — | — | US | disclosed |
| EP-1106606-A2 | N-(3-piperidinylcarbonyl)-beta-alanine derivatives as paf antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-13 | — | — | EP | disclosed |
| WO-1995008536-A1 | N-(3-PIPERIDINYLCARBONYL)-BETA-ALANINE DERIVATIVES AS PAF ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-30 | — | — | WO | disclosed |