Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 14/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502032 | 0.90 | MIF (0.37) | MIFMAOAHDAC6RAB9ANPC1 | |
| SCHEMBL7502020 | 0.90 | MIF (0.39) | MIFHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7502515 | 0.82 | MIF (0.43) | MIFHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7502963 | 0.80 | MIF (0.40) | MIFMAOA | |
| SCHEMBL7503942 | 0.80 | MIF (0.43) | MIFMAOAHDAC6 | |
| SCHEMBL7500699 | 0.79 | MIF (0.47) | MIFMAOARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7506170 | 0.78 | MIF (0.40) | MIFMAOAHDAC6 | |
| SCHEMBL13298912 | 0.77 | MIF (0.59) | MIFHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7503149 | 0.76 | MIF (0.40) | MIFHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7505338 | 0.76 | MIF (0.43) | MIFMAOAHDAC6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920421-B1 | ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | UPJOHN CO (US) | 2002-11-06 | — | — | EP | claimed |