Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 16/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500260 | 0.90 | MIF (0.41) | MIFHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7502032 | 0.89 | MIF (0.37) | MIFHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7503149 | 0.84 | MIF (0.40) | MIFHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7504359 | 0.79 | QDPR (0.46) | MIFHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7507907 | 0.78 | RAB9A (0.48) | MIFHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7505583 | 0.78 | RAB9A (0.45) | MIFHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7502515 | 0.78 | MIF (0.43) | MIFHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7508461 | 0.77 | MIF (0.38) | MIFHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7501060 | 0.77 | RAB9A (0.43) | MIFHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7501044 | 0.77 | RAB9A (0.43) | MIFHDAC6RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920421-B1 | ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | UPJOHN CO (US) | 2002-11-06 | — | — | EP | claimed |
| EP-1173468-A1 | INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000066618-A1 | INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-09 | — | — | WO | disclosed |