Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103731 | 0.85 | P2RX4 (0.31) | — | |
| SCHEMBL14521096 | 0.84 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL11044791 | 0.84 | — | — | |
| SCHEMBL6744618 | 0.80 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL12868789 | 0.79 | P2RX4 (0.35) | — | |
| SCHEMBL583416 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL14456046 | 0.76 | — | — | |
| SCHEMBL2321336 | 0.75 | — | — | |
| SCHEMBL4771757 | 0.75 | EPHX1 (0.33) | CYP19A1 | |
| SCHEMBL1536314 | 0.75 | EPHX1 (0.33) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158982-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-06-12 | — | — | EP | disclosed |
| US-6376496-B1 | TREATMENT OF CANCER | MERCK & CO., INC. | 2002-04-23 | — | — | US | disclosed |
| EP-1158982-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000052134-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-09-08 | — | — | WO | disclosed |