Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.85 |
| ▸ | ITGAV | P06756 | 20/20 | 0.85 |
| ▸ | ITGA2B | P08514 | 20/20 | 0.85 |
| ▸ | ITGB1 | P05556 | 10/20 | 0.77 |
| ▸ | ITGB5 | P18084 | 10/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500443 | 1.00 | ITGB3 (0.85) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7494201 | 0.92 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7494210 | 0.92 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7499194 | 0.91 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7499199 | 0.91 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7500788 | 0.87 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7500781 | 0.87 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7496449 | 0.86 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7496458 | 0.86 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7501719 | 0.86 | ITGB3 (0.84) | ITGB3ITGAVITGA2BITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894084-B1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2002-06-26 | — | — | EP | claimed |
| EP-0894084-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-02-03 | — | — | EP | claimed |
| WO-1997036860-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |
| EP-0894084-B1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2002-06-26 | — | — | EP | disclosed |
| EP-0894084-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-02-03 | — | — | EP | disclosed |
| WO-1997036860-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | disclosed |