Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 5/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509787 | 0.90 | P2RY2 (0.70) | P2RY2 | |
| SCHEMBL7510020 | 0.81 | P2RY2 (0.59) | P2RY2 | |
| SCHEMBL7831877 | 0.81 | KMT2A (0.39) | P2RY2 | |
| SCHEMBL7507329 | 0.80 | P2RY2 (0.41) | P2RY2 | |
| SCHEMBL7504089 | 0.77 | P2RY2 (1.00) | P2RY2 | |
| SCHEMBL7504203 | 0.74 | P2RY2 (0.80) | P2RY2 | |
| SCHEMBL7502865 | 0.74 | P2RY2 (0.80) | P2RY2 | |
| SCHEMBL7488455 | 0.73 | ATAD2 (0.40) | P2RY2 | |
| SCHEMBL7505761 | 0.73 | P2RY2 (0.70) | P2RY2 | |
| SCHEMBL7506443 | 0.73 | P2RY2 (0.79) | P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042320-B1 | NEW COMPOUNDS WHICH ARE P2-PURINOCEPTOR 7-TRANSMEMBRANE (TM) G-PROTEIN COUPLED RECEPTOR ANTAGONISTS | ASTRAZENECA UK LTD (GB) | 2002-02-13 | — | — | EP | disclosed |
| US-6218376-B1 | FOR TREATING INFLAMMATORY DISEASES | ASTRAZENECA UK LIMITED (GB) | 2001-04-17 | — | — | US | disclosed |