Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.64 |
| ▸ | CTSK | P43235 | 7/20 | 0.64 |
| ▸ | CTSB | P07858 | 2/20 | 0.64 |
| ▸ | CTSL | P07711 | 2/20 | 0.64 |
| ▸ | ACE | P12821 | 1/20 | 0.61 |
| ▸ | AKT1 | P31749 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950132 | 1.00 | CTSS (0.64) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL6950136 | 1.00 | CTSS (0.64) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL7269746 | 0.92 | CTSS (0.70) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL20976440 | 0.88 | CTSS (0.65) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL5651916 | 0.86 | CTSS (0.64) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL5651920 | 0.86 | CTSS (0.64) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL21473784 | 0.86 | ACE (0.79) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL66220 | 0.86 | ACE (0.79) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL67020 | 0.86 | ACE (0.79) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL606309 | 0.86 | ACE (0.79) | CTSSCTSKCTSBCTSLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0969000-B1 | Process for reducing alpha-amino ketones | KANEKA CORP (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6255522-B1 | USING AS REDUCING AGENT A REACTION PRODUCT OF ORGANOALUMINUM COMPOUND, SULFONATE AND ALCOHOL | KANEKA CORPORATION (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0969000-A1 | PROCESS FOR REDUCING $G(a)-AMINO KETONES | KANEKA CORPORATION (JP) | 2000-01-05 | — | — | EP | disclosed |