SCHEMBL7500758

SCHEMBL7500758

CC(CCN1CCC(Nc2ccccc2)CC1)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.62
PRMT6 Q96LA8 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27570739 0.86
Hydrochloric Acid SCHEMBL27570794 0.84
SCHEMBL5858752 0.83 KDM4E (0.47)
SCHEMBL11932545 0.82 CARM1 (0.63) CARM1PRMT6
SCHEMBL13687233 0.81 BACE1 (0.54)
SCHEMBL27572566 0.81
SCHEMBL14375364 0.81 SIGMAR1 (0.68)
SCHEMBL27570754 0.80 KDM4E (0.46)
SCHEMBL5857422 0.80 KCNA3 (0.53)
SCHEMBL6700772 0.80 KCNA3 (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1265870-A1 NEW CCR5 MODULATORS: BENZIMIDAZOLES OR BENZOTRIAZOLES AstraZeneca AB (SE) 2002-12-18 EP disclosed
WO-2001066525-A1 NEW CCR5 MODULATORS: BENZIMIDAZOLES OR BENZOTRIAZOLES ASTRAZENECA AB (SE) 2001-09-13 WO disclosed