Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.48 |
| ▸ | F2R | P25116 | 11/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506668 | 0.99 | ITGB3 (0.47) | ITGB3ITGA2BF2RBCHEACHE | |
| SCHEMBL7502057 | 0.98 | ITGB3 (0.49) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7441420 | 0.92 | ITGB3 (0.48) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7501427 | 0.91 | ITGB3 (0.51) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7447077 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7498442 | 0.88 | ITGB3 (0.50) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7816444 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7496508 | 0.86 | ITGB3 (0.49) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7501003 | 0.86 | ITGB3 (0.47) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7445660 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BF2RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380215-B1 | FOR PREVENTION AND/OR TREATMENT OF DISEASES CAUSED BY THROMBUS FORMATION SUCH AS ARTERIAL THROMBOSIS, ARTERIAL SCLEROSIS, ISCHEMIC HEART DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2002-04-30 | — | — | US | disclosed |
| EP-0669912-B1 | N-(3-PIPERIDINYLCARBONYL)-BETA-ALANINE DERIVATIVES AS PAF ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-12-05 | — | — | EP | disclosed |
| EP-1106606-A2 | N-(3-piperidinylcarbonyl)-beta-alanine derivatives as paf antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-13 | — | — | EP | disclosed |
| WO-1995008536-A1 | N-(3-PIPERIDINYLCARBONYL)-BETA-ALANINE DERIVATIVES AS PAF ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-30 | — | — | WO | disclosed |