Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.70 |
| ▸ | ITGAV | P06756 | 19/20 | 0.70 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503841 | 0.82 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7542838 | 0.81 | ITGB3 (0.66) | ITGB3ITGAVITGA2B | |
| SCHEMBL6676170 | 0.78 | ITGB3 (0.56) | ITGB3ITGAVITGA2B | |
| SCHEMBL6676168 | 0.78 | ITGB3 (0.56) | ITGB3ITGAVITGA2B | |
| SCHEMBL7333252 | 0.76 | ITGB3 (0.52) | ITGB3ITGAVITGA2B | |
| SCHEMBL7499256 | 0.74 | ITGB3 (0.68) | ITGB3ITGAVITGA2B | |
| SCHEMBL6948601 | 0.73 | ITGB3 (0.61) | ITGB3ITGAVITGA2B | |
| SCHEMBL6948600 | 0.73 | ITGB3 (0.61) | ITGB3ITGAVITGA2B | |
| SCHEMBL6951803 | 0.73 | ITGB3 (0.73) | ITGB3ITGAVITGA2B | |
| SCHEMBL2786598 | 0.72 | ITGB3 (0.52) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762882-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-09-11 | — | — | EP | claimed |
| EP-0762882-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-03-19 | — | — | EP | claimed |
| WO-1996000574-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | claimed |
| US-6458784-B1 | PHARMACEUTICALLY ACTIVE BENZODIAZAPINE COMPOUNDS OF FORMULA (I) ARE DISCLOSED. THESE COMPOUNDS INHIBIT THE VITRONECTIN RECEPTOR AND ARE USEFUL FOR TREATMENT OF OSTEOPOROSIS. | SMITHKLINE BEECHAM CORPORATION | 2002-10-01 | — | — | US | disclosed |
| EP-0762882-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-0762882-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-03-19 | — | — | EP | disclosed |
| WO-1996000574-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | disclosed |