SCHEMBL7501295

SCHEMBL7501295

c1cnc(SCCc2ccc(C3CCNCC3OCc3ccc4ccccc4c3)cc2)nc1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6041935 0.91 REN (0.68) REN
SCHEMBL6043061 0.88 REN (0.54) REN
SCHEMBL7081908 0.88 REN (0.75) REN
Hydrochloric Acid SCHEMBL7568370 0.87 REN (0.74) REN
SCHEMBL8204726 0.83 REN (0.78) REN
SCHEMBL7077090 0.83 REN (0.60) REN
SCHEMBL7080887 0.82 REN (0.77) REN
SCHEMBL6041682 0.82 REN (0.71) REN
SCHEMBL6960173 0.82 REN (0.83) REN
SCHEMBL6959229 0.82 REN (0.83) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002076440-A2 METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES ELAN PHARMACEUTICALS, INC. (US) 2002-10-03 WO disclosed
EP-0863875-A1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY F. HOFFMANN-LA ROCHE AG (CH) 1998-09-16 EP disclosed
WO-1997009311-A1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY F. HOFFMANN-LA ROCHE AG (CH) 1997-03-13 WO disclosed