Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.54 |
| ▸ | F2R | P25116 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846012 | 0.94 | ITGB3 (0.60) | ITGB3ITGA2BF2RALDH1A1LMNA | |
| SCHEMBL7498595 | 0.89 | ITGB3 (0.48) | ITGB3ITGA2BF2RKMT2A | |
| SCHEMBL7499581 | 0.86 | ITGB3 (0.48) | ITGB3ITGA2BF2RALDH1A1 | |
| SCHEMBL7501495 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BF2RALDH1A1LMNA | |
| SCHEMBL7843158 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BF2R | |
| SCHEMBL7500173 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2BF2R | |
| SCHEMBL7846014 | 0.84 | ITGB3 (0.51) | ITGB3ITGA2BF2RALDH1A1LMNA | |
| SCHEMBL7500224 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2BF2R | |
| SCHEMBL7492116 | 0.81 | ITGB3 (0.54) | ITGB3ITGA2BF2R | |
| SCHEMBL7501790 | 0.81 | ITGB3 (0.64) | ITGB3ITGA2BF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380215-B1 | FOR PREVENTION AND/OR TREATMENT OF DISEASES CAUSED BY THROMBUS FORMATION SUCH AS ARTERIAL THROMBOSIS, ARTERIAL SCLEROSIS, ISCHEMIC HEART DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2002-04-30 | — | — | US | disclosed |
| EP-1106606-A2 | N-(3-piperidinylcarbonyl)-beta-alanine derivatives as paf antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0669912-A1 | N-(3-PIPERIDINYLCARBONYL)-BETA-ALANINE DERIVATIVES AS PAF ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-06 | — | — | EP | disclosed |
| WO-1995008536-A1 | N-(3-PIPERIDINYLCARBONYL)-BETA-ALANINE DERIVATIVES AS PAF ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-30 | — | — | WO | disclosed |