SCHEMBL7501618

SCHEMBL7501618

CCCOc1ccc(C(C=NOC(C)c2ccccc2C(=NOC)C(=O)OC)=NOC)c(F)c1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.40
KAT6A Q92794 2/20 0.35
LMNA P02545 1/20 0.32
CRBN Q96SW2 1/20 0.32
PARP14 Q460N5 1/20 0.32
PARP10 Q53GL7 1/20 0.32
FAAH O00519 1/20 0.31
MAOB P27338 1/20 0.31
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7502694 0.94 HIF1A (0.42) HIF1AKAT6ALMNAPARP14PARP10
SCHEMBL7545134 0.92 KAT6A (0.34) HIF1AKAT6ALMNACRBNPARP14
SCHEMBL7494764 0.92 HIF1A (0.40) HIF1AFAAH
SCHEMBL7504420 0.90 HIF1A (0.38) HIF1ALMNA
SCHEMBL7741770 0.90 KAT6A (0.33) HIF1AKAT6ALMNACRBNPARP14
SCHEMBL7500395 0.88 HIF1A (0.39) HIF1ALMNAFAAH
SCHEMBL8538331 0.87 HIF1A (0.37) HIF1ALMNA
SCHEMBL6704054 0.87 HIF1A (0.36) HIF1A
SCHEMBL7492778 0.86 HIF1A (0.36) HIF1A
SCHEMBL7504773 0.86 LMNA (0.36) HIF1AKAT6ALMNAPARP14PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6420423-B1 PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH BAYER AKTIENGESELLSCHAFT (DE) 2002-07-16 US disclosed
EP-1207152-A2 Pesticides Bayer Aktiengesellschaft (DE) 2002-05-22 EP disclosed
US-5985921-A OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS NOVARTIS CORPORATION (US) 1999-11-16 US disclosed
EP-0865424-A1 PESTICIDES Novartis AG (CH) 1998-09-23 EP disclosed
WO-1997020809-A1 PESTICIDES NOVARTIS AG (CH) 1997-06-12 WO disclosed