Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501707 | 1.00 | CYP1B1 (0.50) | CYP1B1ESR1ESR2MAPTMAOB | |
| SCHEMBL7500978 | 0.86 | F3 (0.53) | CYP1B1ESR1ESR2MAPTMAOB | |
| SCHEMBL7501752 | 0.86 | KDM4E (0.51) | CYP1B1MAPTMAOBMAOARAB9A | |
| SCHEMBL7500993 | 0.86 | F3 (0.53) | CYP1B1ESR1ESR2MAPTMAOB | |
| SCHEMBL7501747 | 0.86 | KDM4E (0.51) | CYP1B1MAPTMAOBMAOARAB9A | |
| SCHEMBL7503829 | 0.85 | CYP1B1 (0.50) | CYP1B1MAPTMAOBMAOARAB9A | |
| SCHEMBL7503643 | 0.85 | SMN1; SMN2 (0.56) | CYP1B1MAPTMAOBMAOALMNA | |
| SCHEMBL3041754 | 0.85 | CXCL12 (0.40) | MAPTRAB9AALDH1A1NPC1MAPK1 | |
| SCHEMBL7503648 | 0.85 | SMN1; SMN2 (0.56) | CYP1B1MAPTMAOBMAOALMNA | |
| SCHEMBL3041751 | 0.85 | CXCL12 (0.40) | MAPTRAB9AALDH1A1NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924202-B1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-6071943-A | IMMUNOMODULATORS WHICH SUPPRESS SPECIFIC CYTOKINES, FOR AUTOIMMUNE DISEASES | SSP CO. LTD. (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0924202-A1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP Co., Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |