Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.39 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501752 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1TLK2CYP2D6XDH | |
| SCHEMBL7502776 | 0.89 | RAB9A (0.55) | KDM4EALDH1A1TLK2CYP2D6MAPT | |
| SCHEMBL7502771 | 0.89 | RAB9A (0.55) | KDM4EALDH1A1TLK2CYP2D6MAPT | |
| SCHEMBL7500993 | 0.88 | F3 (0.53) | KDM4EALDH1A1MAPTRAB9ACXCL12 | |
| SCHEMBL7500978 | 0.88 | F3 (0.53) | KDM4EALDH1A1MAPTRAB9ACXCL12 | |
| SCHEMBL7503829 | 0.86 | CYP1B1 (0.50) | KDM4EALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL3041751 | 0.86 | CXCL12 (0.40) | KDM4EALDH1A1TLK2MAPTRAB9A | |
| SCHEMBL3041754 | 0.86 | CXCL12 (0.40) | KDM4EALDH1A1TLK2MAPTRAB9A | |
| SCHEMBL7503643 | 0.86 | SMN1; SMN2 (0.56) | ALDH1A1TLK2MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL7503648 | 0.86 | SMN1; SMN2 (0.56) | ALDH1A1TLK2MAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924202-B1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-6071943-A | IMMUNOMODULATORS WHICH SUPPRESS SPECIFIC CYTOKINES, FOR AUTOIMMUNE DISEASES | SSP CO. LTD. (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0924202-A1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP Co., Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |