Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496146 | 0.93 | KCNH2 (0.40) | KCNH2HRH3KDM4EALDH1A1LMNA | |
| SCHEMBL7501715 | 0.90 | KCNH2 (0.42) | KCNH2HRH3KDM4EALDH1A1LMNA | |
| SCHEMBL9211202 | 0.88 | KDM4E (0.43) | KDM4EALDH1A1LMNAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL7494575 | 0.85 | KCNH2 (0.34) | KCNH2HRH3KDM4EALDH1A1LMNA | |
| SCHEMBL9207351 | 0.85 | MEN1 (0.39) | KCNH2 | |
| SCHEMBL7847276 | 0.84 | KCNH2 (0.51) | KCNH2HRH3KDM4EALDH1A1LMNA | |
| SCHEMBL9212277 | 0.83 | CACNA1F (0.40) | KCNH2 | |
| SCHEMBL7496654 | 0.82 | KCNH2 (0.37) | KCNH2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL7501610 | 0.82 | KCNH2 (0.37) | KCNH2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL7494369 | 0.82 | KCNH2 (0.37) | KCNH2KDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944385-B1 | USE OF 7-(1-AMINOMETHYL-2-OXA-7-AZA-BICYCLO 3.3.0]OCT-7-YL)-QUINOLONE CARBOXYLIC ACID AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES FOR TREATING HELICOBACTER PYLORI INFECTIONS AND THE GASTRODUODENAL DISEASES ASSOCIATED THEREWITH | BAYER AG (DE) | 2002-10-16 | — | — | EP | disclosed |