Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 16/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494472 | 0.94 | GSK3B (0.36) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9207351 | 0.94 | MEN1 (0.39) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL8924239 | 0.90 | CACNA1F (0.52) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9228860 | 0.90 | MEN1 (0.32) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL7494369 | 0.87 | KCNH2 (0.37) | POLBKCNH2MEN1KMT2ATOP2A | |
| SCHEMBL7501610 | 0.87 | KCNH2 (0.37) | POLBKCNH2MEN1KMT2ATOP2A | |
| SCHEMBL7496654 | 0.87 | KCNH2 (0.37) | POLBKCNH2MEN1KMT2ATOP2A | |
| Hydrochloric Acid SCHEMBL9214724 | 0.86 | KCNH2 (0.45) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL7494469 | 0.85 | GSK3B (0.46) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9214867 | 0.84 | ALDH1A1 (0.42) | POLBKCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589318-B1 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| EP-0589318-A2 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |