Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 2/20 | 0.56 |
| ▸ | CCNC | P24863 | 1/20 | 0.55 |
| ▸ | CDK8 | P49336 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509008 | 0.87 | HTR1A (0.60) | GAKCCNCCDK8SMN1; SMN2MEN1 | |
| SCHEMBL7500265 | 0.81 | CCNC (0.64) | CCNCCDK8SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7506331 | 0.81 | CCNC (0.82) | GAKCCNCCDK8SMN1; SMN2MEN1 | |
| SCHEMBL7504535 | 0.81 | CCNC (0.64) | GAKCCNCCDK8SMN1; SMN2MEN1 | |
| SCHEMBL15966216 | 0.79 | GAA (0.52) | SMN1; SMN2MEN1KMT2AMAPTTP53 | |
| SCHEMBL1581183 | 0.76 | ATM (0.56) | SMN1; SMN2MEN1MAPK1KMT2AMAPT | |
| SCHEMBL1855953 | 0.75 | CCNC (0.55) | GAKCCNCCDK8HTR1AADRA1D | |
| SCHEMBL1861045 | 0.75 | CCNC (0.55) | GAKCCNCCDK8HTR1AADRA1D | |
| SCHEMBL5549300 | 0.75 | FERMT2 (0.68) | GAKCCNCCDK8HTR1AADRA1D | |
| SCHEMBL18500546 | 0.75 | KDM4E (0.50) | SMN1; SMN2MEN1KMT2AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |