SCHEMBL7501948

SCHEMBL7501948

CCCN=C=NCCN(CC)CC

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7614612 0.98 CYP1A2 (0.38) CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL6017813 0.84 CYP1A2 (0.52) CYP1A2CYP2D6
SCHEMBL132315 0.79
SCHEMBL5028799 0.78 CYP1A2 (0.56) CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL6687210 0.76 CYP1A2 (0.54) CYP1A2CYP2D6
SCHEMBL11592977 0.74 NAAA (0.47) CYP1A2CYP2D6
SCHEMBL1269248 0.73 NAAA (0.44)
SCHEMBL11726344 0.73 NPSR1 (0.34)
SCHEMBL6668505 0.73 NPSR1 (0.31)
SCHEMBL97249 0.73 CYP1A2 (0.67) CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0923585-A1 PHOSPHINATE BASED INHIBITORS OF MATRIX METALLOPROTEASES PFIZER INC. (US) 1999-06-23 EP disclosed
WO-1998003516-A1 PHOSPHINATE BASED INHIBITORS OF MATRIX METALLOPROTEASES PFIZER INC. (US) 1998-01-29 WO disclosed