Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5089153 | 0.90 | PTGS2 (0.55) | PTGS2PTGS1PTGDR2NR4A2 | |
| SCHEMBL7504823 | 0.89 | PTGS2 (0.53) | PTGS2PTGS1CA2PTGDR2CA1 | |
| SCHEMBL6002048 | 0.82 | PTGS2 (0.50) | PTGS2PTGS1CA2MAOAMAOB | |
| SCHEMBL6002489 | 0.82 | PTGS2 (0.50) | PTGS2PTGS1CA2MAOAMAOB | |
| SCHEMBL7504997 | 0.81 | PTGS2 (0.63) | PTGS2PTGS1CA2PTGDR2MAOA | |
| SCHEMBL7499074 | 0.81 | PTGS2 (0.62) | PTGS2PTGS1CA2PTGDR2MAOA | |
| SCHEMBL216120 | 0.80 | PTGS2 (0.53) | PTGS2PTGS1PTGDR2 | |
| SCHEMBL7501237 | 0.78 | PTGS2 (0.61) | PTGS2PTGS1CA2MAOAMAOB | |
| SCHEMBL7505500 | 0.78 | PTGS2 (0.61) | PTGS2PTGS1CA2MAOAMAOB | |
| SCHEMBL9029716 | 0.77 | PTGS2 (0.59) | PTGS2PTGS1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699192-B1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2002-07-24 | — | — | EP | claimed |