Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 5/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | FAP | Q12884 | 2/20 | 0.30 |
| ▸ | HCK | P08631 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908528 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL2715582 | 0.87 | — | — | |
| SCHEMBL994220 | 0.81 | EPHX2 (0.46) | METAP1KDM1ADPP4DPP7KMT2A | |
| SCHEMBL6127326 | 0.81 | EPHX2 (0.46) | METAP1KDM1ADPP4DPP7KMT2A | |
| SCHEMBL750354 | 0.81 | METAP1 (0.40) | METAP1KDM1ADPP4DPP7 | |
| SCHEMBL11922743 | 0.80 | — | — | |
| SCHEMBL991936 | 0.80 | DPP4 (0.43) | DPP4DPP7FAP | |
| SCHEMBL991948 | 0.79 | EPHX1 (0.42) | METAP1KDM1ADPP4DPP7KMT2A | |
| SCHEMBL17347050 | 0.78 | DPP7 (0.46) | DPP4DPP7FAP | |
| Hydrochloric Acid SCHEMBL3512222 | 0.78 | ALDH1A1 (0.44) | DPP4DPP7KMT2AFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439174-B1 | 4-IMIDAZOLIN-2-ONE COMPOUNDS AS p38 MAP KINASE INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-21 | — | — | EP | disclosed |