Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 8/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26695081 | 0.85 | PTPN1 (0.41) | PDE4BNR1H2NR1H3PTPN1SCN4A | |
| SCHEMBL27630382 | 0.85 | MEN1 (0.38) | GHSRALDH1A1ADORA1 | |
| SCHEMBL31667836 | 0.85 | MEN1 (0.38) | GHSRALDH1A1ADORA1 | |
| SCHEMBL9699056 | 0.84 | PDE4B (0.40) | PDE4BGHSRNR1H2NR1H3PTPN1 | |
| SCHEMBL31667801 | 0.80 | PDE4B (0.38) | PDE4BGHSRNR1H2NR1H3PTPN1 | |
| SCHEMBL18084466 | 0.79 | NR1H2 (0.45) | PDE4BNR1H2NR1H3PTPN1SCN4A | |
| SCHEMBL26981387 | 0.79 | NR1H2 (0.45) | PDE4BNR1H2NR1H3PTPN1SCN4A | |
| SCHEMBL31482666 | 0.79 | NR1H2 (0.45) | PDE4BNR1H2NR1H3PTPN1SCN4A | |
| SCHEMBL22820950 | 0.78 | NPC1 (0.38) | NR1H2NPC1 | |
| SCHEMBL4147539 | 0.78 | NPC1 (0.39) | NR1H2NR1H3PTPN1SCN4ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |