Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 11/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752906 | 0.96 | PRCP (0.47) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL16499294 | 0.92 | PRCP (0.50) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL749667 | 0.92 | PRCP (0.50) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL15405447 | 0.91 | PRCP (0.51) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL1293611 | 0.89 | PRCP (0.45) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL204202 | 0.89 | PRCP (0.45) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL6126277 | 0.88 | PRCP (0.43) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL12098594 | 0.86 | CYP3A4 (0.59) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL15274593 | 0.86 | LPL (0.40) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL16921672 | 0.86 | LPL (0.40) | PRCPNR1I2ABCB11CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |