Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Allopurinol SCHEMBL3739112 | 0.67 | ALDH1A1 (0.50) | ALDH1A1PARP1 | |
| Allopurinol SCHEMBL2565655 | 0.65 | ALDH1A1 (0.48) | ALDH1A1PARP1 | |
| SCHEMBL8278866 | 0.64 | PARP1 (0.46) | ALDH1A1PARP1HSD17B10 | |
| Oxypurinol SCHEMBL8258215 | 0.64 | PARP1 (0.38) | ALDH1A1PARP1 | |
| SCHEMBL3759284 | 0.64 | HCAR2 (0.46) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL19236510 | 0.64 | CYP1A2 (0.49) | ALDH1A1HSD17B10 | |
| SCHEMBL19152891 | 0.63 | KMT2A (0.44) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL7013359 | 0.62 | ALDH1A1 (0.44) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL18238092 | 0.60 | ALDH1A1 (0.33) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL2473003 | 0.60 | ALDH1A1 (0.64) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181292-A1 | PYROZOLO [3,4-D][1,2,3] TRIAZINES WITH AN ANTICONVULSIVE ACTION AND METHODS FOR PRODUCING THE SAME | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2002-02-27 | — | — | EP | claimed |
| US-6316448-B1 | Pyrazolo[3,4-d][1,2,3] troazines having anticonvulsant activity and process for their preparation | ZENTARIS GMBH (DE) | 2001-11-13 | — | — | US | claimed |
| WO-2000073309-A1 | PYROZOLO [3,4-D][1,2,3] TRIAZINES WITH AN ANTICONVULSIVE ACTION AND METHODS FOR PRODUCING THE SAME | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2000-12-07 | — | — | WO | claimed |
| EP-1181292-A1 | PYROZOLO [3,4-D][1,2,3] TRIAZINES WITH AN ANTICONVULSIVE ACTION AND METHODS FOR PRODUCING THE SAME | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2002-02-27 | — | — | EP | disclosed |
| EP-1181292-A1 | PYROZOLO [3,4-D][1,2,3] TRIAZINES WITH AN ANTICONVULSIVE ACTION AND METHODS FOR PRODUCING THE SAME | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2002-02-27 | — | — | EP | disclosed |
| US-6316448-B1 | Pyrazolo[3,4-d][1,2,3] troazines having anticonvulsant activity and process for their preparation | ZENTARIS GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6316448-B1 | Pyrazolo[3,4-d][1,2,3] troazines having anticonvulsant activity and process for their preparation | ZENTARIS GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| WO-2000073309-A1 | PYROZOLO [3,4-D][1,2,3] TRIAZINES WITH AN ANTICONVULSIVE ACTION AND METHODS FOR PRODUCING THE SAME | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2000-12-07 | — | — | WO | disclosed |
| WO-2000073309-A1 | PYROZOLO [3,4-D][1,2,3] TRIAZINES WITH AN ANTICONVULSIVE ACTION AND METHODS FOR PRODUCING THE SAME | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2000-12-07 | — | — | WO | disclosed |