Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508160 | 0.80 | GAA (0.46) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL19342841 | 0.78 | TAAR1 (0.66) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL4168491 | 0.72 | TAAR1 (0.70) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL4170645 | 0.72 | TAAR1 (0.70) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL30147114 | 0.72 | TAAR1 (0.70) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL4168488 | 0.72 | TAAR1 (0.70) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL8515123 | 0.72 | SLC6A4 (0.74) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL28521100 | 0.72 | CYP3A4 (0.68) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL23016555 | 0.71 | CYP3A4 (0.72) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| Machilin A SCHEMBL10343221 | 0.71 | TAAR1 (0.74) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634408-B1 | DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-01-02 | — | — | EP | disclosed |
| EP-0634408-A1 | DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-01-18 | — | — | EP | disclosed |