Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.38 |
| ▸ | MARS1 | P56192 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513609 | 0.87 | GAA (0.35) | CETPMARS1KMT2AP2RY14PSEN1 | |
| SCHEMBL7515846 | 0.87 | UTS2R (0.37) | CETPMARS1KMT2APSEN1PSEN2 | |
| SCHEMBL7506981 | 0.86 | EEF2K (0.38) | CETPMARS1KMT2ANOTUMPTGER4 | |
| SCHEMBL7516740 | 0.85 | NOTUM (0.35) | CETPMARS1KMT2ANOTUMPTGER4 | |
| SCHEMBL7517203 | 0.85 | GAA (0.39) | CETPMARS1KMT2ANOTUMPTGER4 | |
| SCHEMBL5752911 | 0.81 | KMT2A (0.41) | CETPMARS1KMT2ANOTUMGAA | |
| SCHEMBL29572389 | 0.81 | KMT2A (0.41) | CETPMARS1KMT2ANOTUMGAA | |
| SCHEMBL7515836 | 0.80 | PPARG (0.33) | CETPMARS1KMT2ANOTUMGAA | |
| SCHEMBL7513619 | 0.80 | PTGDR2 (0.38) | CETPMARS1KMT2ANOTUMGAA | |
| SCHEMBL7506976 | 0.80 | PTGER1 (0.37) | CETPKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051173-A4 | DERIVATIVES OF 1,3,4-OXADIAZOLONE | BRISTOL MYERS SQUIBB CO (US) | 2002-07-31 | — | — | EP | claimed |
| EP-1051173-A1 | DERIVATIVES OF 1,3,4-OXADIAZOLONE | Bristol-Myers Squibb Company (US) | 2000-11-15 | — | — | EP | claimed |
| US-6034113-A | ANTIISCHEMIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-03-07 | — | — | US | claimed |
| WO-1999038510-A1 | DERIVATIVES OF 1,3,4-OXADIAZOLONE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-08-05 | — | — | WO | claimed |
| US-6034113-A | ANTIISCHEMIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-03-07 | — | — | US | disclosed |