Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MARS1 | P56192 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515836 | 0.86 | PPARG (0.33) | NOTUMGAAMARS1KMT2ACETP | |
| SCHEMBL7515846 | 0.86 | UTS2R (0.37) | NOTUMGAAMARS1KMT2ACETP | |
| SCHEMBL7517203 | 0.86 | GAA (0.39) | NOTUMGAAMARS1KMT2ACETP | |
| SCHEMBL7506972 | 0.85 | CETP (0.38) | NOTUMGAAMARS1KMT2ACETP | |
| SCHEMBL7513609 | 0.85 | GAA (0.35) | NOTUMGAAMARS1KMT2ACETP | |
| SCHEMBL7506981 | 0.83 | EEF2K (0.38) | NOTUMGAAMARS1KMT2ACETP | |
| SCHEMBL7513619 | 0.83 | PTGDR2 (0.38) | NOTUMGAAMARS1KMT2ACETP | |
| SCHEMBL5752911 | 0.80 | KMT2A (0.41) | NOTUMGAAMARS1KMT2ACETP | |
| SCHEMBL29572389 | 0.80 | KMT2A (0.41) | NOTUMGAAMARS1KMT2ACETP | |
| SCHEMBL7508387 | 0.78 | PTGER1 (0.40) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051173-A4 | DERIVATIVES OF 1,3,4-OXADIAZOLONE | BRISTOL MYERS SQUIBB CO (US) | 2002-07-31 | — | — | EP | claimed |
| EP-1051173-A1 | DERIVATIVES OF 1,3,4-OXADIAZOLONE | Bristol-Myers Squibb Company (US) | 2000-11-15 | — | — | EP | claimed |
| US-6034113-A | ANTIISCHEMIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-03-07 | — | — | US | claimed |
| WO-1999038510-A1 | DERIVATIVES OF 1,3,4-OXADIAZOLONE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-08-05 | — | — | WO | claimed |
| US-6034113-A | ANTIISCHEMIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-03-07 | — | — | US | disclosed |