Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 14/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CALML3 | P27482 | 1/20 | 0.34 |
| ▸ | SDHA | P31040 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503523 | 0.90 | MAOA (0.39) | MIFMAOAMAOBLMNAPTGS1 | |
| SCHEMBL7505315 | 0.87 | MIF (0.38) | MIFEGFRRAB9A | |
| SCHEMBL7501963 | 0.83 | MIF (0.50) | MIFMAOAMAOBRAB9A | |
| SCHEMBL7507033 | 0.82 | MIF (0.42) | MIFMAOAMAOBLMNARAB9A | |
| SCHEMBL7502963 | 0.82 | MIF (0.40) | MIFMAOAMAOB | |
| SCHEMBL7502877 | 0.81 | MIF (0.46) | MIFRAB9A | |
| SCHEMBL7502515 | 0.80 | MIF (0.43) | MIFRAB9A | |
| SCHEMBL7502340 | 0.80 | MIF (0.51) | MIFMAOAMAOBLMNAPTGS1 | |
| SCHEMBL6397343 | 0.80 | MAOA (0.59) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6397336 | 0.80 | MAOA (0.59) | MAOAMAOBLMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990136-A | EFFECTIVE AGAINST GRAMPOSITIVE AEROBIC BACTERIA, E.G. MULTIPLY-RESISTANT STAPHYLOCOCCI AND STREPTOCOCCI, AS WELL AS ANAEROBIC ORGANISMS, E.G. BACTEROIDES, CLOSTRIDIA, MYCOBACTERIUM TUBERCULOSIS AND MYCOBACTERIUM AVIUM | PHARMACIA & UPJOHN COMPANY (US) | 1999-11-23 | — | — | US | claimed |
| EP-0920421-B1 | ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | UPJOHN CO (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6093736-A | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY | 2000-07-25 | — | — | US | disclosed |
| US-5990136-A | EFFECTIVE AGAINST GRAMPOSITIVE AEROBIC BACTERIA, E.G. MULTIPLY-RESISTANT STAPHYLOCOCCI AND STREPTOCOCCI, AS WELL AS ANAEROBIC ORGANISMS, E.G. BACTEROIDES, CLOSTRIDIA, MYCOBACTERIUM TUBERCULOSIS AND MYCOBACTERIUM AVIUM | PHARMACIA & UPJOHN COMPANY (US) | 1999-11-23 | — | — | US | disclosed |