Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 18/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 18/20 | 0.50 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750659 | 0.90 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL751743 | 0.80 | HCRTR1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL2135121 | 0.70 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL752475 | 0.69 | HCRTR1 (0.61) | HCRTR1HCRTR2 | |
| SCHEMBL751030 | 0.69 | HCRTR1 (0.52) | HCRTR1HCRTR2 | |
| SCHEMBL752840 | 0.69 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL4535385 | 0.67 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL4542034 | 0.67 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL4542031 | 0.67 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL4535387 | 0.67 | HCRTR1 (1.00) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430004-A2 | NOVEL OXAZOLIDINONE DERIVATIVES AND THEIR USE AS OREXIN RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2012-03-21 | — | — | EP | claimed |
| WO-2010131192-A2 | NOVEL OXAZOLIDINONE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-11-18 | — | — | WO | claimed |