Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663507 | 0.84 | KDM4E (0.50) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7497895 | 0.83 | EDNRA (0.73) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8043916 | 0.82 | EDNRA (0.75) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8663465 | 0.82 | EDNRA (0.46) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7494105 | 0.81 | EDNRA (0.47) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8043443 | 0.80 | EDNRA (0.46) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7501755 | 0.79 | EDNRA (0.44) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7502700 | 0.78 | EDNRA (0.43) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3834405 | 0.76 | EDNRA (0.81) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3839819 | 0.75 | EDNRA (0.72) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776325-B1 | NOVEL USE AND NOVEL DERIVATIVES OF IMIDAZOLE, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2002-11-20 | — | — | EP | claimed |