Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494105 | 0.97 | EDNRA (0.47) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7496887 | 0.92 | EDNRA (0.46) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7496855 | 0.89 | EDNRA (0.47) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8663507 | 0.88 | KDM4E (0.50) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7496900 | 0.85 | EDNRA (0.64) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8043446 | 0.84 | EDNRA (0.59) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8046639 | 0.84 | EDNRA (0.65) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3838925 | 0.83 | EDNRA (0.46) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7496869 | 0.81 | EDNRA (0.66) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7494119 | 0.80 | EDNRA (0.60) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143774-A | DRUGS AS HYPOTENSIVE AGENTS | HOECHST MARION ROUSSEL (FR) | 2000-11-07 | — | — | US | disclosed |