Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 11/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.35 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | ADAM33 | Q9BZ11 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7117906 | 1.00 | QDPR (0.39) | QDPRNAMPTWNT3ASUV39H2ADAM10 | |
| SCHEMBL7125301 | 0.91 | NAMPT (0.49) | NAMPTWNT3ACDK7CDK13CDK12 | |
| SCHEMBL7126216 | 0.91 | NAMPT (0.49) | NAMPTWNT3ACDK7CDK13CDK12 | |
| SCHEMBL7122767 | 0.87 | NAMPT (0.39) | QDPRNAMPT | |
| SCHEMBL7130227 | 0.87 | NAMPT (0.39) | QDPRNAMPT | |
| SCHEMBL7118426 | 0.82 | CCNT1 (0.39) | NAMPTWNT3AMMP2MMP3MMP14 | |
| SCHEMBL7122724 | 0.76 | QDPR (0.40) | QDPRNAMPTWNT3A | |
| SCHEMBL7124582 | 0.76 | QDPR (0.40) | QDPRNAMPTWNT3A | |
| SCHEMBL8308386 | 0.73 | CYP2D6 (0.30) | — | |
| SCHEMBL19297504 | 0.70 | QDPR (0.49) | QDPRNAMPTWNT3ASUV39H2ADAM10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912561-B1 | 3-PHENYL-FURAN-(5H)-2-ONE AND DIHYDROFURAN-2-ONE DERIVATIVES AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2002-12-04 | — | — | EP | disclosed |
| US-6110936-A | A BACTERICIDE TREATING A BACTERIAL INFECTION IN A WARM BLOODED ANIMAL | ZENECA LIMITED (GB) | 2000-08-29 | — | — | US | disclosed |