Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CCNC | P24863 | 2/20 | 0.60 |
| ▸ | CDK8 | P49336 | 2/20 | 0.60 |
| ▸ | CCR1 | P32246 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | FERMT2 | Q96AC1 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500265 | 0.85 | CCNC (0.64) | CYP1A2CCNCCDK8CCR1PKM | |
| SCHEMBL7503073 | 0.83 | CCNC (0.81) | CYP1A2CCNCCDK8CCR1PKM | |
| SCHEMBL7506331 | 0.82 | CCNC (0.82) | CYP1A2CCNCCDK8PKMKDM4E | |
| SCHEMBL7835537 | 0.81 | PKM (0.54) | CYP1A2CCR1PKMFERMT2KDM4E | |
| SCHEMBL7500391 | 0.81 | CYP1A2 (0.78) | CYP1A2CCNCCDK8CCR1PKM | |
| SCHEMBL7513234 | 0.80 | CCR1 (0.62) | CYP1A2CCNCCDK8CCR1PKM | |
| SCHEMBL7509966 | 0.80 | CYP1A2 (0.57) | CYP1A2CCNCCDK8CCR1FERMT2 | |
| SCHEMBL7505545 | 0.79 | CCNC (0.63) | CYP1A2CCNCCDK8CCR1PKM | |
| SCHEMBL7504559 | 0.79 | CYP1A2 (0.70) | CYP1A2CCNCCDK8CCR1PKM | |
| SCHEMBL7505362 | 0.78 | CCNC (0.58) | CCNCCDK8KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |